3-[6-bromo-2-fluoro-3-(1H-pyrazolo[3,4-c]pyridazin-3-ylmethyl)phenoxy]-5-chlorobenzonitrile

This compound is a synthetic small molecule with the molecular formula C₁₉H₁₀BrClFN₅O and a monoisotopic mass of approximately 456.97 Da. It features a pyrazolopyridazine core linked via a methylene bridge to a phenoxy group substituted with bromo and fluoro substituents, as well as a chlorobenzonitrile moiety. The structure is consistent with annulated pyrazole derivatives that have been studied for antiviral activity, particularly as inhibitors targeting the Gag–Pol polyprotein of HIV‑1. The compound has been referenced in structural studies (PDB ligand code: PZL), indicating its use in biochemical or biophysical research related to HIV‑1 enzyme inhibition[8][5]. There is no evidence it has reached clinical development or approval.

Other names

3-[6-bromo-2-fluoro-3-(1H-pyrazolo[3,4-c]pyridazin-3-ylmethyl)phenoxy]-5-chlorobenzonitrileBenzonitrile, 3-[6-bromo-2-fluoro-3-(1H-pyrazolo[3,4-c]pyridazin-3-ylmethyl)phenoxy]-5-chloro-